Murphy is a hard-living, hard-drinking, disaffected twenty-something with a penchant for cigarettes and casual sex. She's also blind. Murphy lives with her best friend, Jess, and (more reluctantly) her guide dog, Pretzel, whose presence she resents. Her parents, Hank and Joy, own a guide dog school, a venture they opened hoping it would give Murphy a job with some purpose. Murphy's closest friend is a teen named Tyson, whose kindness and intelligence are going to waste. Then she become the only witness to the murder of her drug-dealing friend. After the police dismiss her story, she sets out to find the killer.