Poppy Montgomery stars as Carrie Wells, an NYPD detective with a rare ability that makes her memory so flawless that every place, every conversation, every joy and every heartbreak is forever embedded in her mind, ready to be accessed at a moment's notice. Carrie's memory helped her and her partner (and former boyfriend) Det. Al Burns close a staggering number of murder cases in Queens, which catches the eye of Eliot Delson, head of the Major Crimes Section of the NYPD. Carrie and Al agree to leave Queens to join Eliot's team in Manhattan, though Carrie forces him to bring on Joanne Webster, a brilliant medical examiner well-known to Eliot for her acerbic personality. Armed with her unique ability and backed up by the people she trusts the most, Carrie now helps protect the citizens of New York, with each case more memorable than the last.