Raj and Howard double-date and the latter is flushed with embarrassment after Raj's girlfriend reveals a secret she knows about Howard. Meanwhile, Sheldon is at loose ends when he begins to believe he's wasted his life trying to prove string theory.
George starts dating a college friend who, thanks to Jerry, thinks George is now a marine biologist. Elaine's electronic organizer injures a person after being launched from a limo by a Russian novelist.
Abishola is nervous about Dele's trip to Nigeria with his father. Bob creates a guidebook on Nigeria for Dele that he proudly calls "Sights and Bites."
Sheldon gets a dorm room all to himself. Meemaw gains an unwanted business partner.
Leonard volunteers to sign for a package in an attempt to make a good impression on Penny, but when he enlists Sheldon for help, his attempt at chivalry goes terribly awry.
After James fails to answer a call during a family crisis, he and Astrid find themselves at a boiling point with a growing list of frustrations toward one another.
Bob reconsiders his future at MaxDot and seeks advice from an unexpected source. Abishola questions Bob's erratic behavior.
A foster care worker is reported as missing, but after he ends his own life, the MPU starts to investigate a pregnant woman he was seen with who has been missing for two years. Meanwhile, Sidney follows Keith and fears he may be dangerous.
Lea and Shaun get a quick lesson in parenting when they rush to help an injured dog; Dr. Danica Powell secretly performs an operation on a friend that could jeopardize her career.